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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734336
Species: Mus musculus
RGD Object: Gene
Symbol: Cd86
Name: CD86 antigen
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd86decreases expressionEXP 6480464CTDresveratrol results in decreased expression of CD86 mRNA; resveratrol results in decreased expression of CD86 proteinPMID:14996416 PMID:22962611
Cd86increases expressionISOCD86 (Homo sapiens)6480464CTDresveratrol results in increased expression of CD86 proteinPMID:15135313
Cd86increases expressionISOCd86 (Rattus norvegicus)6480464CTDresveratrol results in increased expression of CD86 mRNA; resveratrol results in increased expression of CD86 proteinPMID:15827377 PMID:25905778
Cd86multiple interactionsISOCD86 (Homo sapiens)6480464CTD[resveratrol co-treated with Lipopolysaccharides] results in increased expression of CD86 proteinPMID:15135313
Cd86multiple interactionsISOCd86 (Rattus norvegicus)6480464CTD[resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNAPMID:25905778
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