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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734037
Species: Homo sapiens
RGD Object: Gene
Symbol: COL2A1
Name: collagen type II alpha 1 chain
Acc ID: CHEBI:8502
Term: 6-propyl-2-thiouracil
Definition: A pyrimidinethione consisting of uracil in which the 2-oxo group is substituted by a thio group and the hydrogen at position 6 is substituted by a propyl group.
Chemical ID: MESH:D011441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
COL2A1affects expressionISOCol2a1 (Rattus norvegicus)6480464CTDPropylthiouracil affects the expression of COL2A1 mRNAPMID:24780913
COL2A1decreases expressionISOCol2a1 (Rattus norvegicus)6480464CTDPropylthiouracil results in decreased expression of COL2A1 mRNAPMID:36843608
COL2A1increases expressionISOCol2a1 (Rattus norvegicus)6480464CTDPropylthiouracil results in increased expression of COL2A1 mRNAPMID:22504374
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