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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734037
Species: Homo sapiens
RGD Object: Gene
Symbol: COL2A1
Name: collagen type II alpha 1 chain
Acc ID: CHEBI:20993
Term: aldehydo-D-glucosamine
Definition: The open-chain form of D-glucosamine.
Chemical ID: MESH:D005944
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
COL2A1affects expressionEXP 6480464CTDGlucosamine analog affects the expression of COL2A1 mRNAPMID:17337215
COL2A1increases expressionEXP 6480464CTDGlucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNAPMID:16300972 PMID:18321735
COL2A1multiple interactionsEXP 6480464CTDGlucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]PMID:17337215 PMID:18321735
COL2A1multiple interactionsISOCol2a1 (Rattus norvegicus)6480464CTDGlucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]PMID:17109745
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