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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733900
Species: Mus musculus
RGD Object: Gene
Symbol: Rad50
Name: RAD50 double strand break repair protein
Acc ID: CHEBI:35456
Term: cadmium dichloride
Definition: A cadmium coordination entity in which cadmium(2+) and Cl(-) ions are present in the ratio 2:1. Although considered to be ionic, it has considerable covalent character to its bonding.
Chemical ID: MESH:D019256
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rad50decreases expressionEXP 6480464CTDCadmium Chloride results in decreased expression of RAD50 mRNAPMID:15501611
Rad50increases expressionEXP 6480464CTDCadmium Chloride results in increased expression of RAD50 mRNAPMID:11958953
Rad50multiple interactionsEXP 6480464CTDMT1 affects the reaction [Cadmium Chloride results in increased expression of RAD50 mRNA]; MT2 affects the reaction [Cadmium Chloride results in increased expression of RAD50 mRNA]PMID:11958953
Rad50decreases expressionISORAD50 (Homo sapiens)6480464CTDCadmium Chloride results in decreased expression of RAD50 mRNAPMID:26472689
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