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GENE - TERM ANNOTATION REPORT

RGD ID: 733483
Species: Homo sapiens
RGD Object: Gene
Symbol: MTHFR
Name: methylenetetrahydrofolate reductase
Acc ID: DOID:5419
Term: schizophrenia
Definition: A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/Schizophrenia "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MTHFRsusceptibilityIAGP 6893466RGDDNA:transition:cds:g.677C>T (human) 
MTHFRsusceptibilityIAGP 7240710OMIM  
MTHFR EXP 11554173CTDCTD Direct Evidence: marker/mechanismPMID:16641680 PMID:17074966 PMID:18583979
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:25736335 PMID:25741868 PMID:28492532
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:16199547 PMID:25736335 PMID:25741868 PMID:28492532
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:18523009 PMID:25741868 PMID:28492532
MTHFR IAGP (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens) or (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:25741868 PMID:28492532
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:25741868
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:19810817 PMID:25741868 PMID:28492532
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:15048559 PMID:25736335 PMID:25741868 PMID:26872964 PMID:28492532
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:10923034 PMID:12733064 PMID:21778025 PMID:25079578 PMID:25736335 PMID:25741868 PMID:26025547 PMID:26872964 PMID:27743313 PMID:28492532 PMID:7726158
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:25736335 PMID:25741868 PMID:27743313 PMID:28492532 PMID:29246599
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:12673793 PMID:25736335 PMID:25741868 PMID:28492532 PMID:33089527 PMID:34214447 PMID:35322348 PMID:35499206
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: SchizophreniaPMID:10679944 PMID:25736335 PMID:25741868 PMID:27743313 PMID:28492532 PMID:7920641
MTHFR IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Schizophrenia, susceptibility toPMID:10677336 PMID:10958762 PMID:11395038 PMID:11590551 PMID:11742092 PMID:11752418 PMID:11938441 PMID:12560871 PMID:15103709 PMID:15543147 PMID:15951337 PMID:16244782 PMID:18583979 PMID:25227144 PMID:25741868 PMID:25741905 PMID:28492532 PMID:28514598 PMID:9545395
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