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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733293
Species: Homo sapiens
RGD Object: Gene
Symbol: APAF1
Name: apoptotic peptidase activating factor 1
Acc ID: CHEBI:30050
Term: gold(0)
Definition: An elemental gold that has formula Au.
Chemical ID: MESH:D006046
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
APAF1decreases expressionEXP 6480464CTDGold analog results in decreased expression of APAF1 mRNAPMID:36057382
APAF1multiple interactionsEXP 6480464CTD[Polyethyleneimine binds to Gold] which results in decreased expression of APAF1 mRNA; [Quercetin analog co-treated with Gold analog] results in increased expression of APAF1 proteinPMID:27470402 PMID:28433809
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