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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732882
Species: Homo sapiens
RGD Object: Gene
Symbol: NPR1
Name: natriuretic peptide receptor 1
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPR1increases expressionEXP 6480464CTDtitanium dioxide results in increased expression of NPR1 mRNAPMID:34973136
NPR1decreases methylationISONpr1 (Mus musculus)6480464CTDtitanium dioxide results in decreased methylation of NPR1 promoterPMID:35295148
NPR1increases methylationISONpr1 (Mus musculus)6480464CTDtitanium dioxide results in increased methylation of NPR1 genePMID:35295148
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