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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732772
Species: Mus musculus
RGD Object: Gene
Symbol: Birc5
Name: baculoviral IAP repeat-containing 5
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Birc5increases expressionEXP 6480464CTDPhenobarbital results in increased expression of BIRC5 mRNAPMID:19363144 PMID:20403969 PMID:23091169 PMID:33549593
Birc5multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of BIRC5 mRNA; [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNA; [Phenobarbital co-treated with Pregnenolone Carbonitrile co-treated with Diethylnitrosamine] results in increased expression of BIRC5 mRNAPMID:24535843 PMID:33398415
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