GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CIB1 | increases expression | ISO | Cib1 (Mus musculus) | 6480464 | CTD | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CIB1 mRNA | PMID:20230807 | CIB1 | increases response to substance | ISO | Cib1 (Mus musculus) | 6480464 | CTD | CIB1 gene mutant form results in increased susceptibility to 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | PMID:28939911 | CIB1 | multiple interactions | ISO | Cib1 (Mus musculus) | 6480464 | CTD | [Nicotine co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CIB1 mRNA; CIB1 gene mutant form promotes the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased phosphorylation of MAP3K5 protein]; Nicotine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CIB1 mRNA] | PMID:20230807 PMID:28939911 | | ||||||||||||||||||||||
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