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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732147
Species: Homo sapiens
RGD Object: Gene
Symbol: MTHFD1
Name: methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
Acc ID: CHEBI:15414
Term: S-adenosyl-L-methionine
Definition: A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine.
Chemical ID: MESH:D012436
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MTHFD1increases abundanceISOMthfd1 (Mus musculus)6480464CTDMTHFD1 protein results in increased abundance of S-AdenosylmethioninePMID:19033438
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