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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731543
Species: Mus musculus
RGD Object: Gene
Symbol: Nox4
Name: NADPH oxidase 4
Acc ID: CHEBI:17775
Term: 7,9-dihydro-1H-purine-2,6,8(3H)-trione
Definition: An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.
Chemical ID: MESH:D014527
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nox4multiple interactionsEXP 6480464CTD[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 mRNA; [Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 protein; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 mRNA]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of NOX4 protein]PMID:36796188
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