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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731513
Species: Mus musculus
RGD Object: Gene
Symbol: Eif2s1
Name: eukaryotic translation initiation factor 2, subunit 1 alpha
Acc ID: CHEBI:42106
Term: L-1,4-dithiothreitol
Definition: A 1,4-dithiothreitol that has formula C4H10O2S2.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif2s1increases phosphorylationEXP 6480464CTDDithiothreitol results in increased phosphorylation of EIF2S1 proteinPMID:30385349
Eif2s1multiple interactionsEXP 6480464CTDEIF2S1 protein mutant form inhibits the reaction [Dithiothreitol results in increased phosphorylation of EIF2S1 protein]PMID:30385349
Eif2s1increases phosphorylationISOEIF2S1 (Homo sapiens)6480464CTDDithiothreitol results in increased phosphorylation of EIF2S1 proteinPMID:34244458
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