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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731513
Species: Mus musculus
RGD Object: Gene
Symbol: Eif2s1
Name: eukaryotic translation initiation factor 2, subunit 1 alpha
Acc ID: CHEBI:197221
Term: NORCANTHARIDIN
Definition: null
Chemical ID: MESH:C069741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif2s1increases phosphorylationISOEIF2S1 (Homo sapiens)6480464CTDnorcantharidin results in increased phosphorylation of EIF2S1 proteinPMID:34272796
Eif2s1multiple interactionsISOEIF2S1 (Homo sapiens)6480464CTD[norcantharidin co-treated with Paclitaxel] results in increased phosphorylation of EIF2S1 protein; Paclitaxel promotes the reaction [norcantharidin results in increased phosphorylation of EIF2S1 protein]; SIRT7 protein inhibits the reaction [[norcantharidin co-treated with Paclitaxel] results in increased phosphorylation of EIF2S1 protein]PMID:34272796
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