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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731476
Species: Mus musculus
RGD Object: Gene
Symbol: Slc6a1
Name: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Acc ID: CHEBI:18248
Term: iron atom
Definition: An iron group element atom that has atomic number 26.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc6a1decreases expressionISOSlc6a1 (Rattus norvegicus)6480464CTDIron deficiency results in decreased expression of SLC6A1 proteinPMID:18771689
Slc6a1increases expressionISOSlc6a1 (Rattus norvegicus)6480464CTDIron deficiency results in increased expression of SLC6A1 mRNAPMID:18771689
Slc6a1multiple interactionsISOSlc6a1 (Rattus norvegicus)6480464CTD[Iron deficiency co-treated with manganese chloride] results in decreased expression of SLC6A1 mRNA; [Iron deficiency co-treated with manganese chloride] results in decreased expression of SLC6A1 protein; [Iron deficiency co-treated with manganese chloride] results in increased expression of SLC6A1 mRNAPMID:18771689
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