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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730901
Species: Homo sapiens
RGD Object: Gene
Symbol: HMOX1
Name: heme oxygenase 1
Acc ID: CHEBI:34674
Term: dextran sulfate
Definition: A polymer composed of repeating (1->6)-alpha-linked anhydroglucose sulfate units.
Chemical ID: MESH:D016264
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HMOX1decreases expressionISOHmox1 (Mus musculus)6480464CTDDextran Sulfate results in decreased expression of HMOX1 mRNA; Dextran Sulfate results in decreased expression of HMOX1 proteinPMID:30142311 PMID:33974900 PMID:36135333
HMOX1multiple interactionsISOHmox1 (Mus musculus)6480464CTD[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of HMOX1 mRNA; asperuloside inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]; Cholecalciferol inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]; gingerenone A inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]; tussilagone inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 mRNA]; tussilagone inhibits the reaction [Dextran Sulfate results in decreased expression of HMOX1 protein]PMID:29950665 PMID:30142311 PMID:33974900 PMID:36135333
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