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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730881
Species: Homo sapiens
RGD Object: Gene
Symbol: HRAS
Name: HRas proto-oncogene, GTPase
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HRASmultiple interactionsEXP 6480464CTD[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of HRAS gene; [N-hydroxy-4-aminobiphenyl co-treated with Copper] results in increased mutagenesis of HRAS gene; [phenylhydroquinone co-treated with Copper] results in increased mutagenesis of HRAS gene; bathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of HRAS gene]; bathocuproine inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of HRAS gene]; CAT protein inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of HRAS gene]; CAT protein inhibits the reaction [[phenylhydroquinone co-treated with Copper] results in increased mutagenesis of HRAS gene]PMID:10334203 PMID:11275476
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