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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727961
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gtf2i
Name: general transcription factor II I
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gtf2iaffects expressionEXP 6480464CTDbisphenol A affects the expression of GTF2I mRNAPMID:25181051
Gtf2iincreases expressionEXP 6480464CTDbisphenol A results in increased expression of GTF2I mRNAPMID:32145629
Gtf2imultiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of GTF2I mRNAPMID:26496021
Gtf2iaffects methylationISOGtf2i (Mus musculus)6480464CTDbisphenol A affects the methylation of GTF2I promoterPMID:27334623
Gtf2idecreases expressionISOGtf2i (Mus musculus)6480464CTDbisphenol A results in decreased expression of GTF2I mRNAPMID:29161229
Gtf2iincreases expressionISOGTF2I (Homo sapiens)6480464CTDbisphenol A results in increased expression of GTF2I mRNAPMID:33670352
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