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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727803
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cd2ap
Name: CD2-associated protein
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cd2apincreases expressionEXP 6480464CTDDoxorubicin results in increased expression of CD2AP mRNA; Doxorubicin results in increased expression of CD2AP proteinPMID:16636307
Cd2apmultiple interactionsEXP 6480464CTDLisinopril inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein]; Prednisone affects the reaction [Doxorubicin results in increased expression of CD2AP mRNA]; Prednisone inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein]; Tretinoin affects the reaction [Doxorubicin results in increased expression of CD2AP mRNA]; Tretinoin inhibits the reaction [Doxorubicin results in increased expression of CD2AP protein]PMID:16636307
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