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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71049
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hnmt
Name: histamine N-methyltransferase
Acc ID: CHEBI:474180
Term: caspofungin
Definition: A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Chemical ID: MESH:C105417
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hnmtdecreases activityISOHNMT (Homo sapiens)6480464CTDcaspofungin results in decreased activity of HNMT proteinPMID:12921242
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