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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70999
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Decr1
Name: 2,4-dienoyl-CoA reductase 1
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Decr1affects expressionEXP 6480464CTDpirinixic acid affects the expression of DECR1 mRNAPMID:19483382
Decr1increases expressionEXP 6480464CTDpirinixic acid results in increased expression of DECR1 mRNAPMID:16940010 PMID:19162173 PMID:22484513 PMID:27665778 PMID:32741897
Decr1increases expressionISODecr1 (Mus musculus)6480464CTDpirinixic acid results in increased expression of DECR1 mRNAPMID:11798191 PMID:16357043 PMID:17426115 PMID:18301758 PMID:20813756 PMID:23811191
Decr1multiple interactionsISODecr1 (Mus musculus)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of DECR1 mRNAPMID:19710929
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