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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70890
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pgrmc1
Name: progesterone receptor membrane component 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pgrmc1affects expressionEXP 6480464CTDbisphenol A affects the expression of PGRMC1 mRNAPMID:25181051
Pgrmc1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PGRMC1 mRNA; bisphenol A results in decreased expression of PGRMC1 proteinPMID:32145629 PMID:34947998
Pgrmc1multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Testosterone] results in increased expression of PGRMC1 mRNAPMID:26496021
Pgrmc1affects expressionISOPGRMC1 (Homo sapiens)6480464CTDbisphenol A affects the expression of PGRMC1 mRNAPMID:30903817
Pgrmc1decreases expressionISOPGRMC1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of PGRMC1 mRNA; bisphenol A results in decreased expression of PGRMC1 proteinPMID:37084542 PMID:37567409
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