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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdm3a
Name: lysine demethylase 3A
Acc ID: CHEBI:95077
Term: GSK-J4
Definition: A member of the class of aminopyrimidines that is pyrimidine substituted by pyridin-2-yl, 3-ethoxy-3-oxopropylamino, and 1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl groups at positions 2, 4, and 6, respectively. It is an inhibitor of the histone demethylase JMJD3/UTX.
Chemical ID: MESH:C000593030
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdm3aincreases expressionISOKDM3A (Homo sapiens)6480464CTDGSK-J4 results in increased expression of KDM3A mRNAPMID:29301935
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