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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70496
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk14
Name: mitogen activated protein kinase 14
Acc ID: CHEBI:15368
Term: acrolein
Definition: An enal that is prop-2-ene with an oxo group at position 1.
Chemical ID: MESH:D000171
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk14increases phosphorylationEXP 6480464CTD[Acrolein results in increased phosphorylation of MAPK14 protein] which results in increased phosphorylation of ATF2 protein; Acrolein results in increased phosphorylation of MAPK14 proteinPMID:12487375
Mapk14multiple interactionsEXP 6480464CTDSB 203580 inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]PMID:12487375
Mapk14increases phosphorylationISOMAPK14 (Homo sapiens)6480464CTDAcrolein results in increased phosphorylation of MAPK14 proteinPMID:11329622 PMID:11504702 PMID:18951912 PMID:29964147
Mapk14multiple interactionsISOMAPK14 (Homo sapiens)6480464CTDRTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of MAPK14 protein]PMID:11329622
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