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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70492
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nat2
Name: N-acetyltransferase 2
Acc ID: CHEBI:28124
Term: 4,4'-methylene-bis-(2-chloroaniline)
Definition: A chloroaniline that consists of two 2-chloroaniline units joined by a methylene bridge.
Chemical ID: MESH:D008753
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nat2affects bindingISONAT2 (Homo sapiens)6480464CTDMethylenebis(chloroaniline) binds to NAT2 proteinPMID:29180287
Nat2increases acetylationISONAT2 (Homo sapiens)6480464CTDNAT2 protein results in increased acetylation of Methylenebis(chloroaniline); NAT2 protein results in increased acetylation of Methylenebis(chloroaniline) analogPMID:29180287
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