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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69647
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eif4e
Name: eukaryotic translation initiation factor 4E
Acc ID: CHEBI:17234
Term: glucose
Definition: An aldohexose used as a source of energy and metabolic intermediate.
Chemical ID: MESH:D005947
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Eif4eincreases phosphorylationISOEif4e (Mus musculus)6480464CTDGlucose results in increased phosphorylation of EIF4E proteinPMID:19765649
Eif4emultiple interactionsISOEif4e (Mus musculus)6480464CTDGlucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]; resveratrol inhibits the reaction [Glucose promotes the reaction [EIF4E protein binds to EIF4G1 protein]]; resveratrol inhibits the reaction [Glucose results in increased phosphorylation of EIF4E protein]PMID:19765649
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