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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:34595
Term: Butylbenzyl phthalate
Definition: A benzyl ester that has formula C19H20O4.
Chemical ID: MESH:C027561
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1multiple interactionsEXP 6480464CTD[diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with butylbenzyl phthalate] results in decreased expression of and affects the methylation of SREBF1 mRNAPMID:31240115
Srebf1multiple interactionsISOSrebf1 (Mus musculus)6480464CTD[butylbenzyl phthalate co-treated with Dietary Fats] results in increased activity of and results in increased localization of SREBF1 proteinPMID:32905190
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