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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69423
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf1
Name: sterol regulatory element binding transcription factor 1
Acc ID: CHEBI:17992
Term: sucrose
Definition: A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose.
Chemical ID: MESH:D013395
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf1multiple interactionsEXP 6480464CTD[Dietary Fats co-treated with Sucrose] results in increased expression of SREBF1 mRNA; [Dietary Fats co-treated with Sucrose] results in increased expression of SREBF1 protein; Biological Products inhibits the reaction [[Dietary Fats co-treated with Sucrose] results in increased expression of SREBF1 mRNA]; Biological Products inhibits the reaction [[Dietary Fats co-treated with Sucrose] results in increased expression of SREBF1 protein]PMID:31175915
Srebf1multiple interactionsISOSrebf1 (Mus musculus)6480464CTD[lard co-treated with Cholesterol co-treated with Sucrose co-treated with Atrazine] results in increased expression of SREBF1 mRNA; [lard co-treated with Cholesterol co-treated with Sucrose co-treated with Ethinyl Estradiol] results in increased expression of SREBF1 mRNAPMID:24440342
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