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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69406
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pclo
Name: piccolo (presynaptic cytomatrix protein)
Acc ID: CHEBI:28088
Term: genistein
Definition: A 7-hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties.
Chemical ID: MESH:D019833
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pclodecreases methylationEXP 6480464CTDGenistein results in decreased methylation of PCLO genePMID:28505145
Pcloincreases expressionISOPclo (Mus musculus)6480464CTDGenistein results in increased expression of PCLO mRNAPMID:32186404
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