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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69363
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nupr1
Name: nuclear protein 1, transcriptional regulator
Acc ID: CHEBI:2504
Term: aflatoxin B1
Definition: An aflatoxin having a tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h]chromene skeleton with oxygen functionality at positions 1, 4 and 11.
Chemical ID: MESH:D016604
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nupr1decreases expressionEXP 6480464CTDAflatoxin B1 results in decreased expression of NUPR1 mRNAPMID:15890375 PMID:23052194 PMID:23630614
Nupr1decreases expressionISONupr1 (Mus musculus)6480464CTDAflatoxin B1 results in decreased expression of NUPR1 mRNAPMID:19770486
Nupr1increases expressionISONUPR1 (Homo sapiens)6480464CTDAflatoxin B1 results in increased expression of NUPR1 mRNAPMID:21632981 PMID:21641981
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