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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69329
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapt
Name: microtubule-associated protein tau
Acc ID: CHEBI:33629
Term: aluminium(0)
Definition: An elemental aluminium that has formula Al.
Chemical ID: MESH:D000535
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Maptincreases phosphorylationEXP 6480464CTDAluminum results in increased phosphorylation of MAPT proteinPMID:17662457
Maptmultiple interactionsEXP 6480464CTD[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA; Berberine inhibits the reaction [[Cadmium co-treated with Aluminum co-treated with Fluorides] results in increased expression of MAPT mRNA]PMID:29170048
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