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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69325
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Acc ID: CHEBI:77565
Term: 2,3,7,8-tetrabromodibenzodioxine
Definition: An organobromine compound that is dibenzodioxine carrying four bromo substituents at positions 2, 3, 7 and 8.
Chemical ID: MESH:C066841
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11a1decreases expressionISOCYP11A1 (Homo sapiens)6480464CTD2,3,7,8-tetrabromodibenzo-4-dioxin results in decreased expression of CYP11A1 mRNAPMID:17447562
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