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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69325
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp11a1
Name: cytochrome P450, family 11, subfamily a, polypeptide 1
Acc ID: CHEBI:4609
Term: Dimethyl phthalate
Definition: A phthalate ester that has formula C10H10O4.
Chemical ID: MESH:C024629
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp11a1increases expressionEXP 6480464CTDdimethyl phthalate results in increased expression of CYP11A1 mRNAPMID:26472102
Cyp11a1multiple interactionsISOCyp11a1 (Mus musculus)6480464CTD[dimethyl phthalate co-treated with diethyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with Diethylhexyl Phthalate] results in decreased expression of CYP11A1 mRNAPMID:35739735
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