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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69305
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr2f2
Name: nuclear receptor subfamily 2, group F, member 2
Acc ID: CHEBI:41879
Term: dexamethasone
Definition: A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 and 21, a methyl group at position 16 and oxo groups at positions 3 and 20. It is a synthetic member of the class of glucocorticoids.
Chemical ID: MESH:D003907
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr2f2increases expressionEXP 6480464CTDDexamethasone results in increased expression of NR2F2 proteinPMID:22615892
Nr2f2multiple interactionsEXP 6480464CTD[[Dibutyl Phthalate co-treated with Dexamethasone] results in increased expression of NR2F2 protein] which results in decreased abundance of Testosterone; [Dexamethasone results in increased expression of NR2F2 protein] which results in decreased abundance of Testosterone; [Dibutyl Phthalate co-treated with Dexamethasone] results in increased expression of NR2F2 proteinPMID:22615892
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