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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69273
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Socs2
Name: suppressor of cytokine signaling 2
Acc ID: CHEBI:17347
Term: testosterone
Definition: An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
Chemical ID: MESH:D013739
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Socs2decreases expressionISOSocs2 (Mus musculus)6480464CTDTestosterone results in decreased expression of SOCS2 mRNAPMID:15788153
Socs2increases expressionISOSOCS2 (Homo sapiens)6480464CTDTestosterone results in increased expression of SOCS2 mRNAPMID:21592394
Socs2multiple interactionsISOSOCS2 (Homo sapiens)6480464CTD[Testosterone co-treated with Calcitriol] results in increased expression of SOCS2 mRNAPMID:21592394
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