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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69273
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Socs2
Name: suppressor of cytokine signaling 2
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Socs2affects expressionEXP 6480464CTDEstradiol affects the expression of SOCS2 mRNAPMID:32145629
Socs2decreases expressionISOSOCS2 (Homo sapiens)6480464CTDEstradiol results in decreased expression of SOCS2 mRNAPMID:31614463
Socs2increases expressionISOSocs2 (Mus musculus)6480464CTDEstradiol results in increased expression of SOCS2 mRNAPMID:19484750 PMID:25210133
Socs2increases expressionISOSOCS2 (Homo sapiens)6480464CTDEstradiol results in increased expression of SOCS2 mRNAPMID:17272397 PMID:21795739
Socs2multiple interactionsISOSOCS2 (Homo sapiens)6480464CTD[Estradiol co-treated with Progesterone] results in increased expression of SOCS2 mRNAPMID:20660070
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