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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69264
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Shank3
Name: SH3 and multiple ankyrin repeat domains 3
Acc ID: CHEBI:28694
Term: copper atom
Definition: A copper group element atom that has formula Cu.
Chemical ID: MESH:D003300
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Shank3multiple interactionsEXP 6480464CTDCopper inhibits the reaction [Potassium results in increased expression of SHANK3 protein]; Copper inhibits the reaction [zinc chloride results in increased expression of SHANK3 protein]PMID:25007851
Shank3decreases expressionISOShank3 (Mus musculus)6480464CTDCopper results in decreased expression of SHANK3 proteinPMID:25007851
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