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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69229
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rack1
Name: receptor for activated C kinase 1
Acc ID: CHEBI:5132
Term: flutamide
Definition: A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
Chemical ID: MESH:D005485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rack1increases expressionEXP 6480464CTDFlutamide results in increased expression of RACK1 mRNAPMID:24136188
Rack1multiple interactionsISORACK1 (Homo sapiens)6480464CTDFlutamide inhibits the reaction [Dehydroepiandrosterone results in increased expression of RACK1 mRNA]; Flutamide inhibits the reaction [Dehydroepiandrosterone results in increased expression of RACK1 protein]; Flutamide inhibits the reaction [Diethylstilbestrol results in increased expression of RACK1 protein]; Flutamide inhibits the reaction [Nandrolone results in increased expression of RACK1 mRNA]PMID:27239218 PMID:28412309 PMID:32328699
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