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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69201
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP27B1
Name: cytochrome P450 family 27 subfamily B member 1
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP27B1affects activityEXP 6480464CTDEstradiol affects the activity of CYP27B1 proteinPMID:17659868
CYP27B1affects expressionEXP 6480464CTDEstradiol affects the expression of CYP27B1 mRNAPMID:17659868
CYP27B1increases activityEXP 6480464CTDEstradiol results in increased activity of CYP27B1 proteinPMID:15795327
CYP27B1increases expressionEXP 6480464CTDEstradiol results in increased expression of CYP27B1 mRNAPMID:31614463
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