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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp27b1
Name: cytochrome P450, family 27, subfamily b, polypeptide 1
Acc ID: CHEBI:9334
Term: sulfasalazine
Definition: An azobenzene consisting of diphenyldiazene having a carboxy substituent at the 4-position, a hydroxy substituent at the 3-position and a 2-pyridylaminosulphonyl substituent at the 4'-position.
Chemical ID: MESH:D012460
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp27b1decreases expressionISOCYP27B1 (Homo sapiens)6480464CTDSulfasalazine results in decreased expression of CYP27B1 mRNAPMID:15243130
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