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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69101
Species: Homo sapiens
RGD Object: Gene
Symbol: GH1
Name: growth hormone 1
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GH1multiple interactionsEXP 6480464CTDZinc promotes the reaction [GH1 protein binds to PRLR protein]PMID:12915731
GH1multiple interactionsISOGh1 (Rattus norvegicus)6480464CTDGH1 protein inhibits the reaction [Zinc deficiency results in decreased expression of GHR mRNA]; GH1 protein inhibits the reaction [Zinc deficiency results in decreased expression of GHR protein]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [alitretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [alitretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine promotes the reaction [Tretinoin results in increased expression of GH1 mRNA]]]; Zinc inhibits the reaction [Pentetic Acid promotes the reaction [Triiodothyronine results in increased expression of GH1 mRNA]]PMID:10720163 PMID:10985758
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