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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68660
Species: Mus musculus
RGD Object: Gene
Symbol: Bhlhe40
Name: basic helix-loop-helix family, member e40
Acc ID: CHEBI:29866
Term: arsenite(3-)
Definition: An arsenite ion resulting from the removal of all three protons from the hydroxy groups of arsenous acid.
Chemical ID: MESH:C015001
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bhlhe40decreases methylationISOBHLHE40 (Homo sapiens)6480464CTDarsenite results in decreased methylation of BHLHE40 promoterPMID:23974009
Bhlhe40multiple interactionsISOBHLHE40 (Homo sapiens)6480464CTD[sodium arsenite results in increased abundance of arsenite] which results in decreased expression of BHLHE40 mRNAPMID:32076005
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