GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cldn1 | decreases expression | EXP | | 6480464 | CTD | Dextran Sulfate results in decreased expression of CLDN1 protein | PMID:27920472 PMID:37001609 PMID:38648921 | Cldn1 | increases expression | EXP | | 6480464 | CTD | Dextran Sulfate results in increased expression of CLDN1 protein | PMID:36543318 | Cldn1 | multiple interactions | EXP | | 6480464 | CTD | 7-hydroxyl-1-methylindole-3-acetonitrile inhibits the reaction [Dextran Sulfate results in increased expression of CLDN1 protein]; [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein; [SB 203580 co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein; biochanin A inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 protein]; hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in decreased expression of CLDN1 protein] | PMID:27920472 PMID:36543318 PMID:37001609 PMID:38648921 | |
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