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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68420
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dio3
Name: iodothyronine deiodinase 3
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dio3multiple interactionsISODio3 (Mus musculus)6480464CTD[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNAPMID:33484791
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