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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68404
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Epas1
Name: endothelial PAS domain protein 1
Acc ID: CHEBI:82664
Term: iron(0)
Definition: An elemental iron in which the atom has an oxidation state of zero.
Chemical ID: MESH:D007501
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Epas1increases expressionEXP 6480464CTDIron deficiency results in increased expression of EPAS1 proteinPMID:23814049
Epas1multiple interactionsISOEPAS1 (Homo sapiens)6480464CTDIron inhibits the reaction [galangin results in increased expression of EPAS1 protein]; Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein]PMID:17973296
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