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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Acc ID: CHEBI:8069
Term: phenobarbital
Definition: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.
Chemical ID: MESH:D010634
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a2affects expressionISONr5a2 (Mus musculus)6480464CTDPhenobarbital affects the expression of NR5A2 mRNAPMID:23091169
Nr5a2increases expressionISONr5a2 (Mus musculus)6480464CTDPhenobarbital results in increased expression of NR5A2 mRNAPMID:19482888
Nr5a2multiple interactionsISONr5a2 (Mus musculus)6480464CTDNR1I3 protein affects the reaction [Phenobarbital results in increased expression of NR5A2 mRNA]PMID:19482888
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