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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68353
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr5a2
Name: nuclear receptor subfamily 5, group A, member 2
Acc ID: CHEBI:17026
Term: progesterone
Definition: A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
Chemical ID: MESH:D011374
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr5a2decreases abundanceISONr5a2 (Mus musculus)6480464CTDNR5A2 gene mutant form results in decreased abundance of ProgesteronePMID:17409375
Nr5a2increases abundanceISONr5a2 (Mus musculus)6480464CTDNR5A2 protein results in increased abundance of ProgesteronePMID:18628394
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