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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68339
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fads2
Name: fatty acid desaturase 2
Acc ID: CHEBI:35549
Term: perfluorooctanoic acid
Definition: A fluoroalkanoic acid that is perfluorinated octanoic acid.
Chemical ID: MESH:C023036
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fads2increases expressionEXP 6480464CTDperfluorooctanoic acid results in increased expression of FADS2 proteinPMID:34958885
Fads2affects expressionISOFADS2 (Homo sapiens)6480464CTDperfluorooctanoic acid affects the expression of FADS2 mRNAPMID:32068100
Fads2decreases expressionISOFADS2 (Homo sapiens)6480464CTDperfluorooctanoic acid results in decreased expression of FADS2 proteinPMID:26879310
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