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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 632286
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Slc22a8
Name: solute carrier family 22 member 8
Acc ID: CHEBI:3537
Term: cefaloridine
Definition: A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C.
Chemical ID: MESH:D002509
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Slc22a8increases uptakeISOSLC22A8 (Homo sapiens)6480464CTDSLC22A8 protein results in increased uptake of CephaloridinePMID:16098483
Slc22a8multiple interactionsISOSLC22A8 (Homo sapiens)6480464CTDCephaloridine inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]PMID:16098483
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