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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Acc ID: CHEBI:9288
Term: streptozocin
Definition: An N-nitrosourea that is an antibiotic produced by Streptomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.
Chemical ID: MESH:D013311
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abca1multiple interactionsEXP 6480464CTD[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ABCA1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ABCA1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ABCA1 mRNAPMID:35786680
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