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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Acc ID: CHEBI:34372
Term: 4,4'-sulfonyldiphenol
Definition: A sulfone that is diphenyl sulfone in which both of the para hydrogens have been replaced by hydroxy groups.
Chemical ID: MESH:C543008
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abca1decreases expressionISOABCA1 (Homo sapiens)6480464CTDbisphenol S results in decreased expression of ABCA1 mRNAPMID:30352284
Abca1increases expressionISOAbca1 (Mus musculus)6480464CTDbisphenol S results in increased expression of ABCA1 mRNAPMID:30951980
Abca1multiple interactionsISOAbca1 (Mus musculus)6480464CTD[bisphenol S co-treated with LIF protein] results in decreased expression of ABCA1 mRNAPMID:30951980
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